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PRP vs. PRF for Hair Loss: 5 Key Differences with Painless Needle-Free Mesotherapy

prp vs. prf hair treatment hair loss
Published at 27 March 2025
Views 421
Author Zahra Haji
Reading time 10
Last Update May 27, 2025

PRP vs. PRF for Hair Loss: 5 Key Differences with Painless Needle-Free Mesotherapy

Curious about PRP vs. PRF for hair loss? Discover the top 5 differences and see how painless needle-free mesotherapy enhances your results naturally and effectively.

Hair loss treatments have evolved significantly, with Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) emerging as two of the most effective regenerative therapies. These treatments use the body’s own platelets to stimulate hair growth, restore thinning areas, and improve scalp health.

At Azura Clinic, we take hair restoration to the next level with our painless, needle-free mesogun technology, making PRP and PRF treatments more comfortable and effective than ever before.

So, which is better for hair loss—PRP or PRF? Let’s break down their differences and see why PRF combined with needle-free mesotherapy is the ultimate choice for hair restoration.


What is PRP for Hair Loss?

Platelet-Rich Plasma (PRP) is a hair restoration treatment that uses a small sample of the patient’s blood, which is spun in a centrifuge to separate the platelet-rich plasma. This plasma contains high levels of growth factors that stimulate hair follicles, promote circulation, and encourage hair regrowth.

Traditionally, PRP is injected into the scalp with fine needles, which can cause discomfort. However, at Azura Clinic, we use a painless, needle-free mesogun to deliver PRP into the scalp without injections, making the process much more comfortable while maintaining its effectiveness.


What is PRF for Hair Loss?

Platelet-Rich Fibrin (PRF) is a more advanced version of PRP. It follows a similar process but with important differences:

  • The centrifuge spins at a lower speed, preserving more platelets, fibrin, and white blood cells.
  • PRF contains a fibrin matrix, which acts as a scaffold to gradually release growth factors over time (rather than immediately, like PRP).
  • PRF does not require anticoagulants or additives, making it a completely natural and pure treatment for hair regrowth.

At Azura Clinic, we combine PRF with our needle-free mesogun for enhanced hair restoration results, ensuring a pain-free experience and longer-lasting effects.


PRP vs. PRF: Key Differences

1. Platelet Concentration

  • PRP: Contains high platelet levels, but some beneficial white blood cells and fibrin are lost in processing.
  • PRF: Contains even more platelets, fibrin, and white blood cells, promoting superior healing and hair follicle regeneration.

2. Growth Factors and Healing Properties

  • PRP: Delivers an immediate boost of growth factors to the scalp but dissipates quickly.
  • PRF: Releases growth factors slowly over time, continuously nourishing the hair follicles for longer-lasting effects.

3. Fibrin Matrix and Long-Term Release

  • PRP: Lacks a fibrin network, meaning growth factors are absorbed quickly.
  • PRF: Contains a natural fibrin matrix, which sustains growth factor release over several days, providing better follicle stimulation.

4. Effectiveness for Hair Growth

  • PRP: Helps strengthen existing hair and promotes some regrowth.
  • PRF: Stimulates stronger, thicker, and healthier hair growth due to its enhanced healing and regenerative properties.

5. Treatment Frequency

  • PRP: Requires monthly treatments for at least 3–4 sessions to maintain results.
  • PRF: Requires fewer treatments, often just 2–3 sessions per year, making it more convenient and cost-effective in the long run.

Why PRF is the Better Choice for Hair Loss

Higher platelet count → More potent stimulation of hair follicles.
Slow-release growth factors → Longer-lasting hair restoration effects.
More natural approach → No additives or chemicals used.
Fewer treatments required → Less hassle and better long-term value.

While PRP is still an effective option, PRF provides superior results for hair loss, making it the preferred choice for patients looking for natural, long-lasting hair regrowth.


Needle-Free Mesotherapy: The Painless Solution

At Azura Clinic, we use a state-of-the-art, needle-free mesogun to deliver PRP and PRF into the scalp.

🔹 100% Painless → No injections, no discomfort.
🔹 Precise Delivery → Ensures even distribution of growth factors across the scalp.
🔹 No Downtime → Resume normal activities immediately after treatment.

This revolutionary technology eliminates the fear of needles, making hair restoration stress-free and comfortable.

mesogun toskani for painless mesotherapy and prp and prf


Who is a Good Candidate for PRF Hair Restoration?

PRF with needle-free mesotherapy is ideal for:

✅ Men and women experiencing thinning hair or early-stage hair loss.
✅ Individuals with weak or miniaturized hair follicles.
✅ Those who want natural hair restoration without surgery.
✅ Anyone looking for a comfortable, painless alternative to injections.

If you’re unsure whether PRF is right for you, schedule a consultation at Azura Clinic to receive expert guidance.


Conclusion: PRP or PRF?

While PRP and PRF both promote hair growth, PRF’s higher platelet concentration, slow-release growth factors, and fibrin matrix make it the superior choice.

Combined with Azura Clinic’s needle-free mesotherapy, PRF offers:
🌟 Enhanced hair regrowth
🌟 Longer-lasting results
🌟 A completely painless experience

See how we perform our painless PRP and PRF treatments on our Instagram Page @azura_clinic

For more information visit the offical Toskani website

Ready to restore your hair without pain or discomfort? Contact Azura Clinic today to book your PRF hair restoration consultation!

📞 Call: 9096 9096
📍 Visit us in Sarooj

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